KAJIAN AKTIVITAS ANTIOKSIDAN KARDIOPROTEKTIF SEDIAAN POLIHERBAL PADA PASIEN HIPERTENSI DI LAYANAN PRIMER DITINJAU DARI AKSIOLOGI DAN ONTOLOGI

Abstract

This study explores the antioxidant activity and cardioprotective effects of polyherbal preparations in hypertensive patients in primary care from an axiological and ontological perspective. Hypertension is one of the major risk factors for cardiovascular disease, with oxidative stress playing an important role in its pathogenesis. A polyherbal approach utilizing natural ingredients such as moringa (Moringa oleifera), black cumin (Nigella sativa), and gotu kola (Centella asiatica) shows potential as adjunctive therapies. From an ontological perspective, this study focuses on the reality of bioactive compounds and their mechanisms in reducing oxidative stress and protecting cardiovascular function. From an axiological perspective, this study evaluated the value of polyherbal benefits in supporting holistic management of hypertension, especially in primary care. The study used clinical experimental methods and laboratory analysis to measure antioxidant activity, blood pressure, and other cardioprotective parameters. The results showed an increase in antioxidant capacity and a significant decrease in blood pressure, supporting the use of polyherbs as adjunctive therapy. This article emphasizes the importance of a multidisciplinary approach in the development and application of herbal-based therapies.