An Overview of Antihypertensive Combination Therapy Among Patients in the Referral Back Program at the UPTD Puskesmas Kuala Pembuang II, 2025
DOI:
https://doi.org/10.61722/jssr.v4i2.9878Keywords:
Antihypertensive Therapy, Combination Therapy, Referral Back ProgramAbstract
Background: Hypertension is a chronic disease with high prevalence requiring continuous management to prevent cardiovascular complications. The Referral Back Program (PRB) facilitates routine medication services for stabel hypertensive patients at primary health care facilities. Objective: This study aimed to identify the demographic characteristics of hypertensive patients and describe the pattern of combination antihypertensive therapy among PRB patients at UPTD Puskesmas Kuala Pembuang II in 2025. Methods: A descriptive non-experimental study with a quantitative approach was conducted using retrospective data from the PRB register. The total sample consisted of 170 hypertensive patients. Results: Most patients were female and belonged to the 55-64 years age group. Combination therapy was used more frequently than monotherapy, with the Amlodipine and Candesartan combination being the most commonly prescribed regimen. The most frequently used single therapies were Amlodipine and Candesartan. Conclusion: Combination antihypertensive therapy was more predominantly used than monotherapy among PRB patients at UPTD Puskesmas Kuala Pembuang II, with patients predominantly female and in the older age group.
References
Amaris, N., Suprapti, S., & Trilestari, T. (2022). Gambaran penggunaan obat antihipertensi pada pasien hipertensi di Puskesmas Kotagede II bulan November–Desember 2020. INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal), 6(2), 65.
Cahyadi, R. I., Wijono, C. O., Adithia, F. K., Sani’ah, N. L. S. R., Sincihu, Y., Wijono, S., dkk. (2024). Gambaran kepatuhan minum obat penderita hipertensi Dusun Sumberame, Kecamatan Wringinanom. Community Development Journal: Jurnal Pengabdian Masyarakat, 5(2), 3591–3597.
Destiara H.Z., Riris D.R. (2017). Relationship between knowledge and hypertension history with blood pressure control in elderly. Jurnal Berkala Epidemiologi 5 (2), 174-184.
Haldi, T., Pristianty, L., & Hidayati, I. R. (2021). Hubungan pengetahuan dan sikap pasien hipertensi terhadap kepatuhan penggunaan obat amlodipin di Puskesmas Arjuno Kota Malang. Jurnal Farmasi Komunitas, 8(1), 27–31.
Kartini, Amalia, L., Rahmawati, R., Rasdianah, N., Darsono, K., Harissya, Z., Mokodompit, Y., Lisnawati, & Ahmad, Z. F. (2022). Epidemiologi penyakit tidak menular. Eureka Media Aksara.
Kementerian Kesehatan Republik Indonesia. (2019). Pedoman pelayanan kefarmasian pada hipertensi. Direktorat Jenderal Kefarmasian dan Alat Kesehatan, Kementerian Kesehatan RI.
Kementerian Kesehatan Republik Indonesia. (2022). Peraturan Menteri Kesehatan Republik Indonesia Nomor 6 Tahun 2022 tentang Penggunaan Jasa Pelayanan Kesehatan dan Dukungan Biaya Operasional Pelayanan Kesehatan dalam Pemanfaatan Dana Kapitasi Jaminan Kesehatan Nasional pada Fasilitas Kesehatan Tingkat Pertama Milik Pemerintah Daerah. Berita Negara Republik Indonesia Tahun 2022 Nomor 315.
Mahdi, H. (2019). Description of the use of antihypertension drug combinations on outpatients at Unhas Hospital in 2019. (Undergraduate thesis, Hasanuddin University).
Nababan, O. A., Oktadiana, I., Prasetyawan, F., Saristiana, Y., Muslikh, F. A., & Mildawati, R. (2024). Evaluasi penggunaan obat pada pasien hipertensi rawat jalan di Puskesmas “X” Kota Solo. Jurnal Media Akademik (JMA), 2(2), 38–43.
Permata, A., Azzahra, P., Mardianto, R., & Prasetiyo, B. D. (2025). Comparion of the effectiveness of combination therapy (candesartan with amlodipine) and (candesartan with nifedipine) in hypertension patients at Lavalette Hospital Malang. Camellia (Clinical, Pharmaceutical, Analytical, and Pharmacy Community Journal), 4(1).
Pradono, J., Kusumawardani, N., & Rachmalina, R. (2020). Hipertensi: Pembunuh terselubung di Indonesia. Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia.
Putri, L. M., Mamesah, M. M., Iswati, & Sulistyana, C. S. (2023). Risk factors that affecting hypertension incident among adult & elderly in Tambaksari, Surabaya. Journal of Health Management Research, 2(1), 2.
Riyadina, W. (2018). Hipertensi pada wanita menopause. LIPI Press.
Sari, Y. K., & Susanti, E. T. (2016). The correlation of Sexes and Hypertension of Elderly in Nglegok Public Health Centre Kabupaten Blitar . Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery), 3(3), 262–265.
Taslim, T., Betris, Y. A. (2020). Overview of drugs in patients with hypertension at Puskesmas Rawang. Jurnal Riset Kefarmasian Indonesia, 8(2), 70–76.
Udayani, N. N. W., Riastini, N.W., Putra, I. M. A. S. (2017). Differences in the effectiveness of the use of drugs Amlodipin single with a combination of Amlodipin and lisinopril in hypertensive patients hospitalized in “X” hospital 2017. Jurnal Ilmiah Medicamento. 4(2), 131.
Wardhani, J. R. K., Zurriyani, & Cahyadi, E. (2024). Hubungan usia dan jenis kelamin dengan kejadian hipertensi pada pasien rawat jalan di Poliklinik Penyakit Dalam RSUD Meuraxa Banda Aceh. Future Academia: The Journal of Multidisciplinary Research on Scientific and Advanced, 2(4), 903–911.
Wulandari, T. (2019). Pola penggunaan kombinasi dua obat antihipertensi pada pasien hipertensi. JURNAL ILKES (Jurnal Ilmu Kesehatan), 10(1), 77–82.
Yunus, M., Aditya, I. W. C., & Eksa, D. R. (2021). The relationship between age and gender with the incidence of hypertension at the Haji Calling Health Center, Anak Tuha District, Central Lampung Regency. Jurnal Ilmu Kedokteran dan Kesehatan, 8(3), Article 5193.
Zuliani, R. P., & Sulung, N. (2022). Analisis pelaksanaan program rujuk balik di Puskesmas Kota Bukittinggi Tahun 2021. Human Care Journal, 7(1), 104–114.
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